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Patients who did not complete the 48-hour observation period nucynta in the study were assigned 0% improvement .
Reference ID: 2858116 Percentage of Patients Achieving Various Levels of Pain Relief as Measured by Pain Severity at nucynta 48 Hours Compared to Baseline- Post Operative Bunionectomy The proportions of patients who showed reduction in pain intensity at 48 hours of 30% or greater, or 50% or greater were significantly higher in patients treated with NUCYNTA® at each dose versus placebo .
2 End-Stage Degenerative Joint Disease A randomized, double-blind, parallel-group, active- and placebo-controlled, multiple-dose study evaluated the efficacy and safety of 50 mg and 75 mg NUCYNTA® given every 4 to 6 hours during waking hours for 10 days in patients aged 18 to nucynta 80 years, experiencing moderate to severe pain from end stage degenerative joint disease of the hip or knee, defined as a 3-day mean pain score of ≥5 on an 11-point pain intensity scale, ranging from 0 to 10 .
Pain scores were assessed twice daily and nucynta assessed the pain the patient had experienced over the previous 12 hours .
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Eighty-three percent (83%) tapentadol tramadol comparison nucynta grunenthal nucynta blood pressure nucynta not covered by of patients in the tapentadol treatment groups and the placebo group took such analgesia during the study .
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