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Tapentadol is tapentadol a new opioid agonist for chronic pain unresponsive to non-opioid medications .
Morphine is still considered the preferred opioid analgesic for moderate-to-severe pain because of familiarity, availability and cost, other opioids including tapentadol may be used where adverse effects of morphine are tapentadol unacceptable .
The place of tapentadol uspi tapentadol usual dosage tapentadol ldt tapentadol pbs authority nucynta like tapentadol in palliative care is presently uncertain and should be used on specialist More studies are needed to determine long term safety and tolerability of tapentadol .
Tapentadol is a novel synthetic opioid analgesic indicated in treatment of moderate-to-severe chronic tapentadol disabling pain .
It is a centrally acting opioid with two mechanisms of action, including agonism at the µ-opioid receptor and noradrenaline reuptake tapentadol inhibition .
[1] Tapentadol was marketed in two forms: immediate release, used mainly for acute pain management and sustained release tapentadol (SR) for moderate-to-severe chronic pain .
Only tapentadol SR has been approved by the TGA in Australia since tapentadol December 2010 .
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