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CLINICAL STUDIES Heart Failure in Adult Patients The Systolic Heart failure treatment with the If inhibitor ivabradine Trial (SHIFT) was a randomized, double-blind trial comparing Corlanor and placebo in procoralan 6558 adult patients with stable NYHA class II to IV heart failure, left ventricular ejection fraction ≤ 35%, and resting heart rate ≥ 70 bpm .
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