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Adverse events are generally included if they were reported in more than 1% of patients in the purinethol uk purinethol nasıl kullanılır purinethol colitis ulcerosa dosierung purinethol lanvis product monograph or pivotal trials, and/or determined to be clinically important .
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Clinically important side effects are in bold, italics allergy/immunology hypersensitivity (2-3%) blood/bone marrow/ febrile neutropenia anemia (>10%); onset 7-10 days, nadir 14-16 days, recovery 21-28 days leukopenia (>10%); onset 7-10 days, nadir 14-16 days, recovery 21-28 days thrombocytopenia (>10%); onset 7-10 days, nadir 14-16 days, recovery 21-28 days constitutional symptoms dermatology/skin BC Cancer Drug Manual Developed: September 1994 Revised: 1 April 2018 Clinically important side effects are in bold, italics hyperpigmentation (1-10%) emetogenic potential: rare gastrointestinal abdominal cramps (1-10%) anorexia (1-10%) diarrhea (1-10%) intestinal ulceration (<1%) nausea and purinethol colite ulcerosa purinethol nella colite ulcerosa purinethol order online purinethol ficha vomiting (1-10%) stomatitis (1-10%) hepatobiliary/pancreas hepatotoxicity (30%) predisposition to bacterial and parasitic infections metabolic/laboratory hyperuricemia (1-10%) renal/genitourinary renal toxicity (1-10%) secondary malignancy leukemia and myelodysplasia (<1%) due to immunosuppression cysts and polyps (2-6%) sexual/reproductive increased risk of abortion if taken in first trimester of pregnancy tumour lysis syndrome; in rare circumstances, certain patients may be at increased oligospermia, transient Adapted from standard reference15 unless specified otherwise .

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