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Node Negative – Individual Studies: tamoxifen NSABP B-14, a prospective, double-blind, randomized study, compared NOLVADEX to placebo in women with axillary node-negative, estrogen-receptor positive (10 fmol/mg cytosol protein) breast cancer (as adjuvant therapy, following total mastectomy and axillary dissection, or segmental resection, axillary dissection, and breast radiation) .
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One additional buy nolvadex in uk nolvadex drops nolvadex dosage ml nolvadex vs letrozole tamoxifen egis pct randomized study (NATO) demonstrated improved disease-free survival for NOLVADEX compared to no adjuvant therapy following total mastectomy and axillary dissection in postmenopausal women with axillary node-negative breast cancer .
In this study, the benefits of NOLVADEX tamoxifen appeared to be independent of estrogen receptor status .
Duration of Therapy: tamoxifen In the EBCTCG 1995 overview, the reduction in recurrence and mortality was greater in those studies that used tamoxifen for about 5 years than in those that used tamoxifen for a shorter period of therapy .
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