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ARIMIDEX product description

Although there have been no formal interaction studies other than with antipyrine, based on these in vivo and in vitro arimidex and tamoxifen arimidex tablets price in india arimidex quand le prendre arimidex studies, it is unlikely that co-administration of a 1 mg dose of ARIMIDEX with other drugs will result in clinically significant drug inhibition of cytochrome P450-mediated metabolism of the other drugs .
An interaction study with warfarin showed no clinically significant effect of anastrozole on warfarin pharmacokinetics or arimidex anticoagulant activity .
At a median follow-up of 33 months, the combination of arimidex vs tamoxifen arimidex and hair loss arimidex and nolvadex arimidex package insert ARIMIDEX and tamoxifen did not demonstrate any efficacy benefit when compared with tamoxifen in all patients as well as in the hormone receptor-positive subpopulation .
This treatment arm was arimidex discontinued from the trial .
Based on clinical and pharmacokinetic results from the ATAC trial, tamoxifen should not be administered with anastrozole (see CLINICAL PHARMACOLOGY – Drug Interactions and CLINICAL PHARMACOLOGY – Clinical Studies – arimidex Adjuvant Treatment of Breast Cancer in Postmenopausal Women subsections) .
Co-administration of anastrozole and tamoxifen resulted in a reduction of anastrozole plasma levels by 27% compared with those arimidex achieved with anastrozole alone .
Estrogen-containing therapies should not be used with arimidex ARIMIDEX as they may diminish its pharmacologic action .
Drug/Laboratory Test Interactions No clinically significant changes in the results of clinical laboratory tests arimidex have been observed .

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