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The no-effect dose (1 mg/kg) eszopiclone was associated with plasma exposures (AUC) to eszopiclone and (S)-DMZ approximately 3 and 2 times, respectively, plasma exposures in humans at the MRHD in adults .
A total of 287 subjects in double-blind, parallel-group, placebo-controlled clinical trials who received eszopiclone were 65 to 86 years of lunesta dosage 4 mg lunesta better than ambien lunesta food lunesta get you high lunesta liver age .
The overall pattern of adverse events for elderly subjects (median age = 71 years) in 2-week studies with nighttime dosing of 2 mg eszopiclone lunesta plus zoloft eszopiclona vademecum lunesta warnings lunesta cost without insurance lunesta was not different from that seen in younger adults [see Adverse Reactions (6)] .
LUNESTA 2 mg exhibited significant reduction in eszopiclone sleep latency and improvement in sleep maintenance in the elderly population .
Compared with non-elderly adults, subjects 65 years and older had lunesta release date eszopiclone vs alprazolam lunesta zoloft lunesta side effects drugs.com lunesta longer elimination and higher total exposure to eszopiclone .
Therefore, dose reduction is eszopiclone recommended in the elderly patients [see Dosage and Administration (2 . 2), Clinical Pharmacology eszopiclone (12 .
Hepatic Impairment No lunesta side effects dry mouth side effects coming off lunesta lunesta for sleep anxiety lunesta dose adjustment is necessary for patients with mild-to-moderate hepatic impairment .
Exposure was increased in severely impaired patients compared with the healthy lunesta and weight gain how long do lunesta side effects last has lunesta going generic lunesta gaba volunteers .
The dose of LUNESTA should not exceed 2 mg in patients with severe eszopiclone hepatic impairment .

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