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When you are taking Norventyl, it is of importance that your physician or pharmacist know if you are taking any of the following medications: *antipsychotics (medicines for mental illness); *Clonidine (high blood pressure treatment) – using clonidine with Norventyl may increase the CNS depressant effect and increase the chance of serious side effects; *antithyroid agents (treatment of overactive thyroid); *Cimetidine (histamine antagonist) – increased risk of serious side effects; * appetite suppressants (diet pills); * ephedrine (bronchodilator); * epinephrine (glaucoma treatment); * isoproterenol (bronchodilator); * medicines to treat asthma or other breathing problems; *medicines for colds, sinus problems, hay fever or other allergies; *phenylephrine (cough and cold medicine) -using this medicine with Norventyl may increase the risk of serious effects on the heart; *central nervous system (CNS) de-pressants – a combination of these medications may increase the CNS depressant effect; *guanadrel (antihypertensive); or *guanethidine (antihypertensive) – a combination of Norventyl and the antihypertensives may reduce the effectiveness of the antihypertensives; *metoclopramide; or *promethazine; or *rauwolfia alkaloids; or *trimeprazine – tricyclic antidepress-ants may cause certain side effects to be more severe and occur more often; *metrizamide – the risk of seizures may be increased; *monoamine oxidase inhibitors – taking tricyclic antidepressants while you are taking or within 2 weeks of taking nortriptyline monoamine oxidase inhibitors may cause sudden highly elevated body temperature, extremely high blood pressure, severe convulsions, and death; however, sometimes certain of these medicines may be used together under close supervision by your physician .
* Other medical problems – the presence of other medical problems may affect the use of tricyclic nortriptyline antidepressants .

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