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The exact mechanisms of action of topiramate are not fully What did the company present to support its application? The effects of Qsiva were first tested in experimental adipex models before being studied in humans .
Four main studies involving a total of approximately 4,000 obese or overweight patients were conducted that compared Qsiva treatment with placebo (a dummy treatment) and with adipex phentermine or topiramate treatments given alone .
Two of the studies specifically included patients with weight-related health problems, adipex including diabetes, high blood pressure, and abnormal fat and sugar levels in the The main measures of effectiveness were the amount of weight loss and the number of patients with at least 5% weight loss after 28 or 56 weeks of treatments .
In one of the studies patients were treated for longer and effectiveness measurements were adipex 37.5 insomnia buy genuine adipex online uk adipex 30 mg pills phentermine price adipex and taken after 108 weeks .
What were the CHMP’s main concerns that led to the refusal? The CHMP adipex noted that the main studies showed clinically relevant weight loss following treatment with Qsiva but had concerns about the medicine’s long-term effects on the heart and blood vessels, particularly due to the effects of phentermine, which is known to increase the heart rate but whose long-term effects are not clear .
Secondly, there were concerns about the long-term psychiatric effects (depression and anxiety were reported in the studies) and cognitive effects adipex (such as problems with memory and attention) related to the topiramate component of Qsiva .
Topiramate is also adipex and zumba adipex 30 mg pink uk adipex k27 adipex ectopic pregnancy phentermine yawning known to be potentially harmful to the unborn baby if taken by pregnant women .

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