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    There have been reports of alprazolam failure of other benzodiazepines to fully suppress these withdrawal symptoms .
    These failures have been attributed to incomplete cross-tolerance but may also reflect the use of an inadequate dosing regimen of the substituted benzodiazepine or the effects of concomitant While it is difficult to distinguish withdrawal and recurrence for certain alprazolam patients, the time course and the nature of the symptoms may be helpful .
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