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Accumulation alprazolam is minimal .
Metabolism and Excretion: Metabolized by the liver alprazolam (CYP3A4 enzyme system) to an active compound that is subsequently rapidly metabolized .
TIME/ACTION PROFILE (sedation) Contraindications/Precautions Contraindicated in: Hypersensitivity; Cross-sensitivity with other benzodiazepines may exist; Pre-existing alprazolam user reviews xanax only alprazolam g3720 xanax uk documentary xanax withdrawal worse CNS depression; Severe uncontrolled pain; Angle-clo⫽ Canadian drug name .
sure glaucoma; Obstructive sleep apnea or different xanax dosages xanax withdrawal muscle pain xanax 0 25 mg ulotka xanax withdrawal fatal pulmonary disease; Concurrent use with itraconazole or ketoconazole; OB, Lactation: Use in pregnancy or lactation may cause CNS depression, flaccidity, feeding difficulties, and seizures in infant .
Use Cautiously in: Renal impairment(pdose required); Hepatic impairment (p dose required); Concurrent use with nefazodone, fluvoxamine, cimetidine, fluoxetine, hormonal contraceptives, diltiazem, isoniazid, erythromycin, clarithromycin, or grapefruit juice (pdose may be necessary); History of suicide attempt or alcohol/ drug dependence, debilitated patients (pdose required); Pedi: Safety and efficacy not established;pdosage and frequent monitoring required; Geri: Appears on Beers alprazolam list .
Elderly patients haveqsensitivity to benzodiazepines; associated withqrisk of falls and alprazolam excessive CNS effects (pdose required) .
ALPRAZolam (al-pray-zoe-lam) Plate # 0-Composite Adverse Reactions/Side Effects CNS: dizziness, alprazolam drowsiness, lethargy, confusion, hangover, headache, mental depression, paradoxical excitation .
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