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However, as a injecting ambien pills zolpidem tartrate vs lunesta zolpidem same as ambien zolpidem binding site general precaution, these patients should be closely monitored .
08 Zolpidem was administered to rats and mice for 2 years at dietary dosages of 4, 18, ambien and 80 mg/kg/day . 1 Carcinogenesis, mutagenesis, impairment of fertility ambien NDA 19908 FDA SLR 027 Approved labeling 4 . 13 NONCLINICAL TOXICOLOGY ambien names zolpidem tartrate uses zolpidem street value zolpidem category ambient air generic 13 .
In mice, these ambien doses are 26 to 520 times or 2 to 35 times the maximum 10 mg human dose on a mg/kg or mg/m2 basis, respectively .
In rats these doses are 43 ambien to 876 times or 6 to 115 times the maximum 10 mg human dose on a mg/kg or mg/m2 basis, respectively .
No ambien evidence of carcinogenic potential was observed in mice .
Renal liposarcomas were seen in 4/100 rats (3 males, 1 female) receiving 80 mg/kg/day and a renal lipoma was observed in one male rat at ambien the 18 mg/kg/day dose .
Incidence rates of lipoma and liposarcoma for ambien zolpidem were comparable to those seen in historical controls and the tumor findings are thought to be a spontaneous occurrence .
Zolpidem did not have mutagenic activity in several tests including the Ames ambien test, genotoxicity in mouse lymphoma cells in vitro, chromosomal aberrations in cultured human lymphocytes, unscheduled DNA synthesis in rat hepatocytes in vitro, and the micronucleus test in mice .
Impairment of fertility: In a rat reproduction study, the high dose (100 mg base/kg) of zolpidem resulted in irregular estrus cycles and prolonged precoital intervals, but there was no effect on male or female fertility after daily oral doses of 4 to 100 mg base/kg or order zolpidem 10mg pictures of ambien tablets ambien dosage strengths zolpidem tartrate onset of 5 to 130 times the recommended human dose in mg/m2 .

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