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Modafinil administered orally to pregnant rabbits throughout organogenesis at doses of up to 100 mg/kg/day had no effect on embryofetal development; however, the doses used were too low to adequately armodafinil high armodafinil comedown armodafinil drug interactions armodafinil coupon nuvigil drug assess the effects of modafinil on embryofetal development .
In a subsequent developmental toxicity study evaluating doses of 45, 90, and 180 mg/kg/day in pregnant rabbits, the incidences of nuvigil warnings grapefruit juice armodafinil armodafinil tablets side effects nuvigil to get high fetal structural alterations and embryofetal death were increased at the highest dose .
The highest no-effect dose for developmental toxicity (100 mg/kg/day) was associated with a plasma armodafinil AUC less than that in humans at the MRHD of Modafinil administration to rats throughout gestation and lactation at oral doses of up to 200 mg/kg/day resulted in decreased viability in the offspring at doses greater than 20 mg/kg/day, a dose resulting in a plasma armodafinil AUC less than that armodafinil in humans at the MRHD of NUVIGIL .
No effects armodafinil on postnatal developmental and neurobehavioral parameters were observed in surviving offspring .
armodafinil Pregnancy Registry A pregnancy registry has been established to collect information on the pregnancy outcomes of women exposed to NUVIGIL .
Healthcare providers are encouraged to register pregnant patients, or pregnant armodafinil now nuvigil joint pain nuvigil interactions nuvigil drug armodafinil and weed women may enroll themselves in the registry by calling 1-866-404-4106 (toll free) .
3 Nursing Mothers It is not known whether armodafinil nuvigil manufacturer waklert sprzedam nuvigil better than provigil waklert production nuvigil kaiser or its metabolites are excreted in human milk .

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