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Drug interactions

CONTRAINDICATIONS PALEXIA® SR is contraindicated:  in patients with a known hypersensitivity to the active substance, tapentadol, or any component of the product,  in situations where drugs with mu-opioid receptor tapentadol urinary retention nucynta serious side effects tapentadol chemical name tapentadol ukmi agonist activity are contraindicated, i .
patients with significant respiratory depression (in unmonitored settings or the absence of resuscitative equipment), and patients with acute or severe bronchial asthma or hypercapnia,  in any patient who has or is suspected of having paralytic ileus,  in patients with acute intoxication with alcohol, nucynta hypnotics, centrally acting analgesics, or psychotropic drugs (see PRECAUTIONS, Interactions with other medicines),  in patients who are receiving MAO inhibitors or who have taken them within the last 14 days (see PRECAUTIONS, Interactions with other Potential for Abuse As with other drugs that have mu-opioid receptor agonist activity, PALEXIA® SR has a potential for abuse .
This should be considered when prescribing or dispensing PALEXIA® SR in situations where there is concern about an nucynta false positive methadone tapentadol prescribing information tapentadol neuropathic pain increased risk of misuse, abuse, or diversion .
AusPAR Palexia IR Tapentadol CSL Pty Ltd PM-2009-02488-3-1 Date of Finalisation tapentadol bnf tapentadol presentacion tapentadol usos dosis tratamiento nucynta class tapentadol as 17 November 2010 Drugs that have mu-opioid receptor agonist activity may be abused by crushing, chewing, snorting or injecting the product .
Such practices pose a significant risk to the abuser and nucynta may result in overdose or death .

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