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what is clonidine hcl 0.2 mg used for clonidine dosage for sleep in adults clonidine hcl uses why is Except for some dryness of the eyes, no drug-related abnormal ophthalmological findings were recorded and, according to specialized tests such as electroretinography and macular dazzle, retinal function was unchanged .
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Carcinogenesis, Mutagenesis, Impairment of Fertility Chronic dietary administration of clonidine was not carcinogenic to rats (132 weeks) or mice (78 weeks) dosed, respectively, at clonidine up to 46 or 70 times the maximum recommended daily human dose as mg/kg (9 or 6 times the MRDHD on a mg/m2 basis) .
There was no evidence of genotoxicity in the Ames test for mutagenicity or mouse micronucleus test for Fertility of male or female rats was unaffected by clonidine doses as high clonidine as 150 mcg/kg (approximately 3 times MRDHD) .
) Teratogenic Effects: how to use clonidine for withdrawal smoking clonidine clonidine 0.1 mg patch clonidine and seizures Pregnancy Category C . In a separate experiment, fertility of female rats appeared to be affected at dose levels of 500 to 2000 mcg/kg (10 to 40 times the oral MRDHD on a mg/kg basis; 2 to clonidine 8 times the MRDHD on a mg/m2 basis .
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