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Geriatric and Gender: Losartan pharmacokinetics have been investigated in the elderly (65-75 years) cozaar and in both genders .
Plasma concentrations cozaar of losartan and its active metabolite are similar in elderly and young hypertensives .
Plasma concentrations of losartan losartan potassium 100 mg film-coated tablets cozaar comp bivirkninger valsartan und alkohol cozaar were about twice as high in female hypertensives as male hypertensives, but concentrations of the active metabolite were similar in males and females .
No dosage adjustment is necessary (see cozaar DOSAGE AND ADMINISTRATION) .
Race: Pharmacokinetic differences due to race have not been studied (see also PRECAUTIONS, Race and CLINICAL PHARMACOLOGY, Pharmacodynamics and Clinical Effects, Reduction in the Risk of Stroke, Renal Insufficiency: Following oral administration, plasma concentrations and AUCs of losartan and its active metabolite are increased losartan generic side effects hyzaar skin rash losartan 100 mg vademecum cozaar oral tablet 50 mg by 50-90% in patients with mild (creatinine clearance of 50 to 74 mL/min) or moderate (creatinine clearance 30 to 49 mL/min) renal insufficiency .
In this study, renal clearance was reduced by cozaar 100 mg vidal hyzaar and potassium hyzaar monograph losartan 100 mg para sirve order hyzaar 5585% for both losartan and its active metabolite in patients with mild or moderate renal insufficiency .
Neither losartan nor its active metabolite can be removed cozaar by hemodialysis .
No dosage adjustment is necessary for patients with renal impairment unless they are volume-depleted (see cozaar 50 mg.28 tb losartan analogi losartan normon hyzaar allergic reactions losartan y valsartan WARNINGS, Hypotension — VolumeDepleted Patients and DOSAGE AND ADMINISTRATION) .

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