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Experimental and clinical evidences suggested that benzodiazepines could influence immune cell properties, such as phagocyte activity, chemotaxis and the production of superoxide, and cytokines; either by reducing the diazepam stress and anxiety or through stimulation of Peripheral Benzodiazepine Receptors (PBRS) [4] .
These PBRS have been identified mainly diazepam erectile dysfunction diazepam to lorazepam valium brand name 5mg diazepam high dose into the mitochondria of non-neuronal peripheral cells as adrenocortical cells [5] and also, in the cellular components of the immune system, such as monocytes, neutrophils, macrophages [6] .
Ligands of PBRs have been found to regulate activity of genes responsible for biosynthesis diazepam of cholesterol derivatives as corticosterone modulate monocyte functions such as chemotaxis [7,8] .
Also, these ligands have been reported to suppress the production of IL-1, IL-2, IL-6, TNF-α, diazepam 5 mg untuk apa diazepam keeps me awake diazepam for sale diazepam pills bangkok valium IFN-γ, and to increase glucocorticoid production [9] .
Therefore, this diazepam study aims to investigate the possible anti-inflammatory effects of the diazepam on acute and chronic inflammatory responses in the rats with exploring the possible underlying mechanisms involved in these anti-inflammatory actions .
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