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Benzodiazepines are commonly implicated in hepatic diazepam encephalopathy .
Increases in half-life have also been reported in hepatic fibrosis and in both acute and chronic hepatitis (see CLINICAL PHARMACOLOGY: Pharmacokinetics in Special Populations: Hepatic ADVERSE diazepam REACTIONS Side effects most commonly reported were drowsiness, fatigue, muscle weakness, and ataxia .
diazepam The following have also been reported: Central Nervous System: confusion, depression, dysarthria, headache, slurred speech, tremor, vertigo Gastrointestinal System: constipation, nausea, gastrointestinal disturbances Special Senses: blurred vision, diplopia, dizziness Cardiovascular System: hypotension Psychiatric and Paradoxical Reactions: stimulation, restlessness, acute hyperexcited states, anxiety, agitation, aggressiveness, irritability, rage, hallucinations, psychoses, delusions, increased muscle spasticity, insomnia, sleep disturbances, and nightmares .
Inappropriate behavior and other adverse behavioral effects have diazepam been reported when using benzodiazepines .
Should diazepam these occur, use of the drug should be discontinued .
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