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Renal function shall be closely monitored and Lioresal daily dosage lioresal mechanism of action lioresal was ist das lioresal valor buy lioresal online lioresal adjusted accordingly to prevent baclofen toxicity .
Besides discontinuing treatment, unscheduled haemodialysis might be considered as a treatment alternative in lioresal patients with severe baclofen toxicity .
Haemodialysis effectively removes lioresal baclofen from the body, alleviates clinical symptoms of overdose and shortens the recovery time in these patients .
Abrupt discontinuation Anxiety and confusional states, delirium, hallucinations, psychotic disorders, mania, or paranoia, convulsion (status epilepticus), dyskinesia, tachycardia, hyperthermia and – as a rebound phenomenon – temporary aggravation of spasticity have been reported upon the abrupt withdrawal of Lioresal, especially after lioresal long-term medication .
Drug withdrawal reactions including postnatal convulsions in neonates have been reported after intrauterine lioresal exposure to oral Lioresal .
(See “Use in lioresal Pregnancy”) .
For the intrathecal formulation of Lioresal, it has been reported that clinical characteristics of withdrawal may resemble autonomic dysreflexia, infection (sepsis), malignant hyperthermia, neuroleptic-malignant syndrome, or other conditions associated lioresal with a hypermetabolic state or widespread rhabdomyolysis .
Except in overdose-related emergencies or where serious adverse effects have occurred, treatment should, therefore, always be gradually withdrawn by successive lioresal dosage reduction over a period of approximately 1 to 2 weeks .
If withdrawal symptoms occur, restarting baclofen therapy and withdrawing over a longer lioresal period may help to resolve withdrawal problems .voltaren period pain |
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