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In addition to nitroglycerin, 2 major metabolites 1,2- and 1,3-dinitroglycerin, are found nitroglycerin tablets dosage what are the side effects of nitroglycerin nitroglycerin tab in plasma .
Mean peak nitroglycerin 1,2- and 1,3-dinitroglycerin plasma concentrations occur at approximately 15 minutes postdose .
The elimination half-life of 1,2- and nitroglycerin 1,3-dinitroglycerin is 36 and 32 minutes, respectively .
The 1,2- and 1,3-dinitroglycerin metabolites have nitroglycerin been reported to possess approximately 2% and 10% of the pharmacological activity of nitroglycerin .
Higher plasma concentrations of the dinitro metabolites, along with their nearly 10-fold longer elimination halflives, may nitroglycerin interactions nitroglycerin facts nitroglycerin prescription vasodilator nitroglycerin contribute significantly to the duration of pharmacologic effect .
Glycerol mononitrate metabolites nitroglycerin of nitroglycerin are biologically inactive .
Elimination: Nitroglycerin plasma concentrations decrease rapidly with a mean elimination halflife of 2 to nitroglycerin 3 minutes .
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