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Guidelines for use of Oxycodone (Oxycontin®, Oxynorm®)  Guidelines for use  Oral oxycodone may be used for treatment of severe chronic non malignant pain, and moderate  to severe pain caused by malignant disease as an alternative to morphine for the small proportion  oxycodone of patients who develop intolerable adverse effects to morphine where other possible options for  managing opioid adverse effects have been tried and failed . Parenteral  Oxycodone  may  be  used  oxycodone as  an  alternative  to  oral  oxycodone  when  patients  require  parenteral therapy . oxycodone Patients should be prescribed regular oral M/R oxycodone (Oxycontin) (see conversion factor for  changing from Morphine) and liquid or capsular oxycodone (Oxynorm) for breakthrough pain . oxycodone It should be initiated by clinicians with experience in palliative care or as part of the chronic pain  management team only .

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