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Precautions

If doses of prednisolone prednisolone are high, serum potassium should be monitored regularly .
Serious consideration of upper gastrointestinal studies should be contemplated when patients complain of gastric symptoms while on this prednisolone medication .
In general, prolonged therapy above 8 prednisolone mg/day is associated with increased incidence of adverse effects; mental disorders are associated with doses exceeding 40 mg/day .
Drug-induced secondary prednisolone adrenocortical insufficiency may be minimized by gradual reduction of dosage .
This type of relative insufficiency may persist for months after discontinuation of therapy; therefore, prednisolone in any situation of stress occurring during that period, hormone therapy should be reinstated .
Since mineralocorticoid secretion may be impaired, salt and/or mineralocorticoid should be administered prednisolone concurrently .
Hypertrophic cardiomyopathy has been reported after systemic administration of glucocorticosteroids prednisolone in preterm infants .
In infants receiving administration of prednisolone systemic glucocorticosteroids, echocardiograms should be performed to monitor myocardial structure and Growth and development of infants and children on prolonged corticosteroid therapy should be carefully observed .
Administration of corticosteroids to children should be limited to the least amount compatible with que prednisolone prednisone side effects tired prednisolone side effects high dose prednisolone an effective therapeutic regimen .
Pediatric patients demonstrate greater susceptibility to corticosteroid-induced HPA axis suppression and Cushing’s syndrome than mature prednisolone patients .
HPA axis suppression, Cushing’s syndrome and intracranial hypertension have been reported in children taking prednisolone oral corticosteroids .

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