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DRUG ABUSE AND DEPENDENCE soma SOMA is not a controlled substance [see Warnings and Precautions (5 .
Discontinuation of carisoprodol in animals or in humans after chronic administration soma can produce withdrawal signs, and there are published case reports of human carisoprodol In vitro studies demonstrate that carisoprodol elicits barbiturate-like effects .
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Monkeys self soma administer carisoprodol .
soma Drug discrimination studies using rats indicate that carisoprodol has positive reinforcing and discriminative effects similar to barbital, meprobamate, and chlordiazepoxide .
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Many of the SOMA overdoses have occurred in the setting of multiple drug overdoses (including drugs of abuse, illegal soma drugs, and alcohol) .

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