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Drug Interactions Losartan, administered for 12 days, cozaar onset peak duration cozaar side effects weight gain valsartan label losartan sivuvaikutukset did not affect the pharmacokinetics or pharmacodynamics of a single dose of warfarin .
Losartan did not affect cozaar the pharmacokinetics of oral or intravenous digoxin .
There is no pharmacokinetic interaction between losartan and que es cozaar 100 mg cozaar rash cozaar insomnia hyzaar onset action losartan 50 mg description hydrochlorothiazide .
Coadministration of cozaar losartan and cimetidine led to an increase of about 18% in AUC of losartan but did not affect the pharmacokinetics of its active metabolite .
Coadministration hyzaar fort prospektüs losartan 100 mg vademecum losartan 50 mg 30 comprimidos losartan y enalapril of losartan and phenobarbital led to a reduction of about 20% in the AUC of losartan and that of its active metabolite .
A somewhat greater interaction (approximately 40% reduction in the Reference ID: 3283103 COZAAR® (LOSARTAN POTASSIUM TABLETS) AUC of active metabolite cozaar and approximately 30% reduction in the AUC of losartan) has been reported with rifampin .
Fluconazole, an inhibitor of cytochrome P450 2C9, decreased the AUC of the active metabolite cozaar by approximately 40%, but increased the AUC of losartan by approximately 70% following multiple doses .
Conversion of cozaar compendium cozaar hypertension losartan 50 mg con hidroclorotiazida cozaar and ibuprofen losartan to its active metabolite after intravenous administration is not affected by ketoconazole, an inhibitor of P450 3A4 .
The AUC of active metabolite following oral cozaar losartan was not affected by erythromycin, another inhibitor of P450 3A4, but the AUC of losartan was increased by 30% .
Pharmacodynamics and Clinical Effects Adult Hypertension Losartan cozaar inhibits the pressor effect of angiotensin II (as well as angiotensin I) infusions .cozaar prescribing information |
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