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Acetaminophen has been associated hydrocodone with cases of acute liver failure, at times resulting in liver transplant and death .
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Risks From Concomitant Use With Benzodiazepines Or Other CNS Depressants Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and hydrocodone acetaminophen 5-325 for migraines hydrocodone heart rate hydrocodone-apap 5mg-325mg qua death [see WARNINGS and PRECAUTIONS; Drug Interactions] .
• Reserve concomitant prescribing of NORCO® and benzodiazepines or other CNS hydrocodone acetaminophen 5-325 high hydrocodone 5-325 pregnancy can hydrocodone cause high liver depressants for use in patients for whom alternative treatment options are inadequate .
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