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Here again we face the imovane problem of the validity of the reported phenomena, which has already been highligh ted with respect to benzodiazepines (16) .
The lack of objective analysis of the phenomenon, the absence of a control group, the consequences of insomnia or of the underlying disease on the cognitive functions and the usual discrepancy between memory complaints and the normality of psychometric tests are the main obstacles to the assessment of the contribution of imovane drugs to side effects (17) .
Complaints imovane concerning nightmares were also reported in a small number of cases (0 .
The majority of these events occurred imovane in patients who had had previous hypnotic medication (7/10), which was discontinued in the 2 days preceding the start ofthe study (6/10) .
These nightmares may have been withdrawal symptoms related to the previous treatment (18) rather than events associated with zopiclone, especially as they appeared in the zopiclone davis drug guide zopiclone heart rate imovane product monograph zopiclone uses que es first day of zopiclone treatment .
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