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NUBAIN did not have mutagenic activity nalbuphine in the AMES test with four bacterial strains, in the Chinese Hamster Ovary HGPRT assays or in the Sister Chromatids Exchange Assay .
However, NUBAIN induced an nalbuphine increased frequency of mutation in the mouse lymphoma assay .
Clastogenic activity was not observed in the mouse micronucleus test of the cytogenicity bone marrow assay buy nalbuphine online ebay buy nalbuphine online philippines buy nalbuphine online english buy in rats .
Impairment of Fertility A reproduction study was performed in male and female rats at subcutaneous doses nalbuphine up to 56 mg/kg/day or 330 mg/m2/day .
NUBAIN did not affect either male or female fertility Usage in Pregnancy Teratogenic Effects: Pregnancy Category B: Reproduction studies have been performed in rats by subcutaneous administration of nalbuphine up to 100 mg/kg/day, or 590 mg/m2/day which is approximately 6 times the MRHD, and in rabbits by intravenous administration of nalbuphine up nalbuphine to 32 mg/kg/day, or 378 mg/m2/day which is approximately 4 times the MRHD .
The results did not reveal evidence of developmental toxicity, including teratogenicity, or harm buy nalbuphine qvc buy nalbuphine online canada buy nalbuphine online dubai buy nalbuphine online to the fetus .
There nalbuphine are, however, no adequate and well-controlled studies in pregnant women .
Because animal reproduction studies are not always predictive of human response, buy nalbuphine online dubai buy nalbuphine online game buy nalbuphine online tv buy nalbuphine this drug should be used during pregnancy only if clearly needed .ketorolac injection dosage adults |
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