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Post-herpetic Neuralgia (PHN) The effectiveness of pregabalin for the management of neuropathic pain was investigated in 5 double blind, placebo-controlled, multi-centre studies with either twice a day (BID) or three lyrica times a day (TID) dosing .
lyrical yosemite widget lyrica kidney damage lyrical themes pregabalin gaba pregabalin kapsule A total of 1250 patients were enrolled in the 5 studies .
To enter the study patients had to have moderate to severe lyrical meter lyrical quotes about love lyrica webmd pregabalin addiction lyrica headache lyrical pain for  3 months (or  6 months in one study) .
The mean duration of PHN for patients in these studies was 3 years (range  1 – lyrica 22 years) .
In the 4 completed studies, the lyrica pfizer lyrical dance to true colors pregabalin edema lyrica valium lyrica vs pregabalin average age was 71 years, the average duration of PHN was 38 months, and the average baseline pain score was 6 .
Concomitant use of analgesics and antidepressants was allowed, provided the regimen was stable and in place at the lyrica time of Table 2 .
Results of the Primary Outcome (Endpoint Mean Pain Scores) for Post-herpetic Neuralgia Study/Treatment Group Study 030 TID [5 weeks] N=255 Pregabalin 75 mg/day (n=84) Pregabalin 150 mg/day (n=83) Study 045 TID [8 weeks] N=238 Pregabalin lyrica 150 mg/day (n=81) Pregabalin 300 mg/day (n=76) Study 127 TID [8 weeks] N=173 Pregabalin 300/600 mg/day* (n=89) Study 132 BID [12 weeks†] N=216 Pregabalin 150 mg/day (n=51) Pregabalin 300 mg/day (n=62) Pregabalin 300/600 mg/day* (n=51) Study 196 BID [13 weeks] N=368 Pregabalin 150 mg/day (n=87) Pregabalin 300 mg/day (n=98) Pregabalin 300/600 mg/day* (n=90) Treatment Comparisons (Pregabalin  Placebo) *Patients randomised to the 300/600 mg/day pregabalin group received either 300 or 600 mg/day based on their CLcr .

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