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27 After identifying the lower and upper limits of efficacy – the points of maximum sensitivity – random-effects DerSimonian-Laird odds ratios and their 95% confidence intervals were used to pool nortriptyline results of the independent studies by means of the software Arcus . Coordinates were then translated into percentage improvement and drug concentrations expressed as nortriptyline withdrawal is nortriptyline used for sleep does nortriptyline make you sleepy ng/ml . 26 Statistical analysis In order to nortriptyline medicine side effects of nortriptyline 10mg tablets nortriptyline dosage for migraine test the existence of a narrow therapeutic range or TW, we used the receiver operating characteristics (ROC) curve as the primary statistical tool .
A Q test of homogeneity or “combinability” for the odds ratios was calculated, indicating that pooling was viable among the selected does nortriptyline help with anxiety nortriptyline dosage for ibs nortriptyline 10 mg para que sirve studies (p> 0 .
Data were broken down from the six included studies into 2×2 contingency tables, presenting the proportion nortriptyline of patients who responded inside the therapeutic window as compared with those who responded outside it .
We also measured nortriptyline the absolute risk reduction (difference in event rates between the control and treatment groups) .
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the number of patients who had to nortriptyline be treated in order to prevent one event, was calculated as the reciprocal of the absolute risk reduction . 28,29 The number of studies (with nortriptyline withdrawal ic nortriptyline hcl nortriptyline nerve pain side effects is amitriptyline null results) needed to overturn the conclusions (fail-safe n) when a significant result was found was also assessed .nortriptyline migraine,
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