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The fact that the oxycodone comparator showed nucynta poor efficacy in the study raises concerns about the validity of the study .
The secondary nucynta efficacy measure, responder analysis, indicated that the proportion of subjects with 50% improvement in the tapentadol SR group was statistically significantly greater (p=0 . 027) nucynta than the response in the placebo group .
The percent of tapentadol tapentadol tablet 100mg nucynta grapefruit nucynta tapentadol 75 mg vs oxycodone palexia dose SR subjects with 30% improvement in tapentadol SR was not statistically significant (p=0 .
Oxycodone CR treatment was statistically significantly nucynta in urine tapentadol australian product information tapentadol overdose symptoms youtube worse for all measures of responders and this once again raises concerns about interpretation and validity of the results .
181) or the overall maintenance period Overall the clinical evaluator considered that this study did nucynta not provide convincing evidence of efficacy of tapentadol SR . Importantly, for subjects with baseline pain intensity scores categorised as moderate, comparison of tapentadol south africa nucynta yahoo answers tapentadol constipation nucynta revenue tapentadol the average pain intensity scores for tapentadol SR and placebo was not statistically significant in either the last week of the maintenance period (p=0 .
It is of major concern that oxycodone nucynta was shown to have such poor efficacy in this study .
This raises concerns about the validity of the nucynta study results .
In addition, results for responder rates and exploratory efficacy nucynta analyses did not consistently support efficacy of tapentadol SR .
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