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The container eszopiclone closure system is satisfactorily described .
The containers proposed for routine storage are those which have been used in the stability studies supporting the re-test Stability studies were carried out lunesta side effects dizziness lunesta or ambien better eszopiclone insomnia elderly lunesta opioid on four commercial batches of eszopiclone kept in the packaging similar to the commercial container under ICH conditions (60 months at 25°C/60% RH and 6 months at 40°C/75% RH) .
Parameters performed lunesta side effects commercial lunesta negative side effects lunesta make you gain weight were appearance, water content, assay (HPLC), enantiomeric purity, impurities, particle size distribution and microbial examination .
Analytical methods and specifications were the same as those eszopiclone used for release testing .
Results demonstrate the chemical and physical stability of eszopiclone under long term and accelerated can lunesta and ambien be taken together lunesta generic vs ambien eszopiclone nedir lunesta coupon conditions .
Additionally, results show that racemization does not occur eszopiclone during storage .
Furthermore, photostability testing was conducted for one batch in accordance with eszopiclone guideline ICH Q1B (option 2 conditions) .
The substance was found to be light eszopiclone sensitive .
Studies conducted when the product is kept in the packaging demonstrated the suitability of the eszopiclone packaging .
Stability studies conducted under forced conditions (acid, basic and oxidative conditions) allowed establishing the eszopiclone main degradation pathways of the molecule .
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