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  • #15484
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    nz/profs/datasheet A Lynn, B Robertshawe motilium Sept 2010 A Lynn, B Robertshawe June 2012 (re-order profile) Printed copies are not controlled and may not be the current version in use Authorised by: Clinical Director Neonatal .
    Canterbury District Health Board Neonatal Services Motilium® Tablets are used to make this extemporaneously prepared Domperidone 1mg/mL Oral motilium Solution .
    Dopamine antagonist, antiemetic Mechanism of Action Domperidone is a dopamine antagonist (blocking both D1 motilium and Dopamine antagonism stimulates gastric emptying, increased rate of intestinal transit time and enhanced strength of oesophageal sphincter contractions .
    The antiemetic effect of domperidone is due to motilium the prokinetic effect on the gastrointestinal tract combined with antagonisation of dopamine receptors in the chemo trigger Domperidone does not readily cross the blood brain barrier .

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