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Thus, Corlanor was evaluated for its effect on heart rate in a multi-center, randomized, double-blind, placebo-controlled trial in procoralan children with symptomatic DCM .
The study collected procoralan data from 116 patients aged 6 months to less than 18 years with DCM in sinus rhythm, NYHA/Ross class II to IV heart failure, and left ventricular ejection fraction ≤ 45% .
Patients had to be clinically stable for at medicament le procoralan procoralan in usa procoralan na icc procoralan mg procoralan wskazania do least 4 weeks and on optimized medical therapy with a resting heart rate (HR) complying with the following criteria: HR ≥ 105 bpm in the age-subset 6–12 months .
HR ≥ 95 bpm in the age-subset procoralan 1–3 years .
HR ≥ 75 procoralan moa procoralan ricetta procoralan zn procoralan vaistai procoralan galino procoralan bpm in the age-subset 3–5 years .
HR ≥ 70 procoralan bpm in the age-subset 5–18 years .
Patients were randomized in a 2:1 ratio to procoralan receive Corlanor or placebo .
Doses of study medication were titrated over a procoralan 2- to 8-week period to achieve a 20% heart rate reduction without inducing bradycardia .
The target heart rate reduction was obtained at the end of the titration period in a significantly higher proportion of procoralan patients with Corlanor vs .
16% respectively; Odds Ratio procoralan = 15; 95% CI = [5; 47]) .
A statistically significant reduction in HR was observed with Corlanor compared to procoralan placebo at the end of the titration period (-23 ± 11 bpm vs .
-2 ± 12 bpm buy ambien online next day delivery medicamento procoralan 5 mg procoralan uso procoralan gefährlich respectively) .
HOW SUPPLIED/STORAGE AND HANDLING procoralan Corlanor 5 mg tablets are formulated as salmon-colored, oval-shaped, film-coated tablets scored on both edges, marked with “5” on one face and bisected on the other face .

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