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The efficacy of Trazodone HCl has been demonstrated in both inpatient and outpatient trazodone settings and for depressed patients with and without prominent anxiety .
a Major Depressive Episode implies a prominent and relatively persistent (nearly every day for at least two weeks) depressed or dysphoric mood that usually interferes with daily functioning, and includes at least four of the following eight symptoms: change in appetite, trazodone change in sleep, psychomotor agitation or retardation, loss of interest in usual activities or decrease in sexual drive, increased fatigability, feelings of guilt or worthlessness, slowed thinking or impaired concentration, and suicidal ideation or attempts . The depressive illness of patients studied corresponds to the Major Depressive Episode criteria of the American Psychiatric Association’s Diagnostic trazodone and Statistical Manual, lll .
Contraindications Trazodone hydrochloride tablets are contraindicated in patients hypersensitive to Warnings Clinical Worsening and Suicide Risk Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or trazodone side effects paranoia molipaxin medication desyrel uso trazodone side effects pregnancy unusual changes in behavior, whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs .
Suicide is a known risk of depression and trazodone 50 mg and weight loss desyrel 50 mg yan etkileri trazodone side effects hiccups trazodone certain other psychiatric disorders, and these disorders themselves are the strongest predictors of suicide .
There has been a longstanding concern, however, that antidepressants may trazodone have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment .

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