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As is true of most CNS6 Reference ID: 4029651 acting drugs, patients receiving Valium should be cautioned against engaging in hazardous occupations requiring complete mental alertness, such as operating machinery or valium driving a motor vehicle .
Drug Interactions The concomitant use of benzodiazepines and opioids increases the risk of respiratory depression because of actions at different diazepam 5 mg for sleep purchase diazepam online valium auditory hallucinations valium benefits receptor sites in the CNS that control respiration .
Benzodiazepines interact at valium GABAA sites and opioids interact primarily at mu receptors .
When benzodiazepines and opioids are combined, the potential for benzodiazepines to significantly worsen valium opioidrelated respiratory depression exists .
Limit dosage and duration of concomitant use of benzodiazepines and opioids, and monitor patients closely for respiratory depression valium and sedation .
Centrally Acting Agents If Valium is to be combined with other centrally acting agents, careful consideration should be given to valium the pharmacology of the agents employed particularly with compounds that may potentiate or be potentiated by the anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, sedative antihistamines, narcotics, barbiturates, MAO inhibitors and other antidepressants .
Concomitant use with alcohol is not recommended due diazepam 10 mg tablet mylan diazepam jrcalc purchase diazepam uk diazepam onset peak duration valium to enhancement of the sedative effect .
Diazepam peak concentrations are valium 30% lower when antacids are administered concurrently .
However, there is no effect on valium the extent of absorption .
The lower peak concentrations appear due to a slower rate valium of absorption, with the time required to achieve peak concentrations on average 20 – 25 minutes greater in the presence of antacids .

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