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49 “Error lunesta and high fat foods eszopiclone reviews eszopiclone france mylan generic lunesta reviews diagnostics from the residuals will be examined to ensure that the assumptions of the model are valid . All other presented calculations (for instance eszopiclone using a non-parametric approach, using transformed variables etc) were solely planned to be conducted for establishing robustness of the primary analysis (for example, RAP, p .
If the assumptions are seriously violated, a transformation of eszopiclone the endpoint or non-parametric methods will be considered to assess the robustness of the analysis .
” lunesta elderly side effects lunesta medicaid will generic lunesta available eszopiclone long term RAP12 . This will be carried out eszopiclone in addition to the parametric analysis . 6 lunesta side effects eyes lunesta drug class eszopiclone en español lunesta available in generic Robustness of the primary analysis, p49-51) .
That is, the different approaches and analyses calculated for the primary endpoint were planned to establish robustness of a primary statistically significant result obtained by a possibly misspecified model and as such were explicitly not designed as pre-tests which would have been part of a two-stage primary analysis strategy, which in contrast would have made eszopiclone adjustment for multiplicity necessary .
It eszopiclone remains an open question whether the primary analysis based on PP and ITT populations as required by ICH E9 would deliver statistically significant results, and whether the model assumptions are met in these populations .
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