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A higher fetal tissue distribution (25% maternal plasma concentration) was crestor muscle side effects crestor blood pressure side effects crestor 40 mg uses does crestor observed in rabbits after a single oral gavage dose of 1 mg/kg on gestation day 18 .
If this drug is administered to a woman with reproductive does crestor work crestor triglycerides crestor 100mg low dose crestor crestor blood pressure potential, the patient should be apprised of the potential hazard to a fetus .
In female rats given oral gavage doses of 5, 15, 50 mg/kg/day rosuvastatin before mating and continuing through day 7 postcoitus results in decreased fetal body weight (female pups) and delayed does crestor cause heartburn generic crestor news how long has crestor been on the market is ossification at the high dose (systemic exposures 10 times human exposure at 40 mg/day based on AUC comparisons) .
3, 1, 3 mg/kg/day from gestation day 6 to lactation day 18 (weaning), exposures equivalent to human exposure at 40 mg/day based on body surface area comparisons, decreased fetal viability and maternal crestor mortality was observed . In pregnant rats given oral gavage doses of 2, 10, 50 mg/kg/day from gestation day 7 through lactation crestor day 21 (weaning), decreased pup survival occurred in groups given 50 mg/kg/day, systemic exposures ≥12 times human exposure at 40 mg/day based on body surface area In pregnant rabbits given oral gavage doses of 0 .
Rosuvastatin was not teratogenic in rats at ≤25 mg/kg/day or in rabbits ≤3 mg/kg/day crestor (systemic exposures equivalent to human exposure at 40 mg/day based on AUC or body surface comparison, respectively) .
It is not crestor known whether rosuvastatin is excreted in human milk .
Studies in lactating rats have crestor demonstrated that rosuvastatin is secreted into breast milk at levels 3 times higher than that obtained in the plasma following oral gavage dosing .

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