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Drug/Laboratory norvasc Test Interactions: None known .
norvasc 5, 1 . Carcinogenesis, Mutagenesis, Impairment of Fertility: Rats and mice treated with amlodipine maleate in the diet for up to two years, at concentrations calculated to provide daily dosage levels of how long does it take for norvasc 5mg to work norvasc category norvasc how long to take effect 0 . norvasc 25, and 2 . 5 amlodipine mg/kg/day showed norvasc maximum dose norvasc 2.5 mg norvasc drug class norvasc heart rate norvasc wiki drug class no evidence ofa carcinogenic effect of the drug .
For the mouse, the highest dose was, on a mg/m2 norvasc basis, similar to the maximum recommended human dose of 10 mg amlodipine/day*) .
For the rat, the highest dose , was on a mg/m2 basis, about twice the maximum norvasc recommended human dose* .
Mutagenicity studies conducted with amlodipine maleate revealed no drug related effects at norvasc either the gene or chromosome level .
There was no effect on the fertility of rats treated orally with amlodipine maleate (males for half life norvasc norvasc brand name norvasc mechanism of action norvasc drug norvasc strengths 64 days and females for 14 days prior to mating) at doses up to 10 mg amlodipine/kg/day (8 times* the maximum recommended human dose of 10 mg/day on a mg/m2 basis) .
Pregnancy Category C: No evidence of teratogenicity or other embryo/fetal toxicity was found when pregnant rats and rabbits were treated orally with amlodipine maleate at doses up to 10 mg amlodipine/kg/day (respectively 8 times* and 23 times* the what does norvasc look like norvasc half life when to take norvasc norvasc fatigue what are the side maximum recommended human dose of 10 mg on a mg/m2 basis) during their respective periods of major organogenesis .

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