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Racemic citalopram was not mutagenic in the in vitro Reference ID: 4036381 mammalian forward gene mutation assay (HPRT) in mouse lymphoma cells or in a coupled in vitro/in vivo unscheduled DNA synthesis (UDS) escitalopram assay in rat liver .
It was not clastogenic in the in vitro escitalopram chromosomal aberration assay in human lymphocytes or in two in vivo mouse micronucleus assays .
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Gestation duration was increased escitalopram at 48 mg/kg/day .
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